Midwife Antonia Maibach (Marion Kracht) has come to feel very much at home at Lake Tegernsee in Bavaria, especially now she has moved in with her boyfriend Dr. Thomas Hellmann (Michael Roll), senior physician at the "Clinic on the Lake". The maternity department now seems to be run entirely by women: Antonia, her best friend Helena (Julia Bremermann) and the head midwife Vroni Stangassinger (Christiane Blumhoff) take care of the pregnant women, the fathers and of course their babies. But soon a male colleague appears to support the three ladies.